Dr Mitchell's search led her, eventually, to a small biotech lab in California that had spent six years developing what they called a "GLP-1 support patch" — a transdermal delivery system designed to help the body's own GLP-1 production stay active past age 50.
The patch — now sold under the name LotusPatch — uses a blend of plant-derived compounds shown in studies to support the body's natural GLP-1 pathway, delivered through the skin in a slow, steady release over 8–12 hours.5
Three things made Dr Mitchell take it seriously:
First, transdermal delivery bypasses the digestive system entirely. Unlike pills that lose 60–80% of their active compounds to stomach acid, the patch delivers actives directly into the bloodstream — the same reason hormone replacement therapy switched to patches decades ago.
Second, the patch supports the body's own GLP-1 production rather than replacing it with a synthetic version. That means no "rebound" weight gain when you stop using it.
Third, the price. At a fraction of the cost of prescription injections, with no doctor's visit required.